LC3-mHTT-IN-AN1
CAS No. 486443-73-6
LC3-mHTT-IN-AN1 ( —— )
产品货号. M21755 CAS No. 486443-73-6
LC3-mHTT-IN-AN1 (Compound AN1) is a mHTT-LC3 linker compound, which interacts with both mutant huntingtin protein (mHTT) and LC3B but not with wtHTT or irrelevant control proteins. LC3-mHTT-IN-AN1 reduces the levels of mHTT in an allele-selective manner in cultured Huntington disease (HD) mouse neurons.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
规格 | 价格/人民币 | 库存 | 数量 |
2MG | ¥1361 | 有现货 |
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5MG | ¥2066 | 有现货 |
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10MG | ¥3062 | 有现货 |
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25MG | ¥5176 | 有现货 |
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50MG | ¥7395 | 有现货 |
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100MG | ¥9963 | 有现货 |
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200MG | 获取报价 | 有现货 |
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500MG | 获取报价 | 有现货 |
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1G | 获取报价 | 有现货 |
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生物学信息
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产品名称LC3-mHTT-IN-AN1
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述LC3-mHTT-IN-AN1 (Compound AN1) is a mHTT-LC3 linker compound, which interacts with both mutant huntingtin protein (mHTT) and LC3B but not with wtHTT or irrelevant control proteins. LC3-mHTT-IN-AN1 reduces the levels of mHTT in an allele-selective manner in cultured Huntington disease (HD) mouse neurons.
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产品描述LC3-mHTT-IN-AN1 (Compound AN1) is a mHTT-LC3 linker compound, which interacts with both mutant huntingtin protein (mHTT) and LC3B but not with wtHTT or irrelevant control proteins. LC3-mHTT-IN-AN1 reduces the levels of mHTT in an allele-selective manner in cultured Huntington disease (HD) mouse neurons.
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同义词——
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通路Autophagy
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靶点Autophagy
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受体——
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研究领域——
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适应症——
化学信息
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CAS Number486443-73-6
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分子量411.04
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分子式C15H9Br2NO3
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纯度>98% (HPLC)
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溶解度DMSO : 125 mg/mL (304.11 mM; Need ultrasonic) H2O : < 0.1 mg/mL (insoluble)
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SMILESBrC1=CC=C(C/2=C1)NC(C2=C/C3=CC(Br)=C(C(O)=C3)O)=O
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Li Z, et al. Allele-selective lowering of mutant HTT protein by HTT-LC3 linker compounds. Nature. 2019 Nov;575(7781):203-209.
产品手册
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